A lot of InkSeine users are early adopters who have gone ahead and grabbed the Windows Desktop Search 4.0 Preview.
However, as these folks are discovering, InkSeine's Personal Search features DO NOT WORK with the Preview. If you want to keep using desktop searches from within InkSeine, avoid the preview or uninstall it if you've already grabbed it.
For details, see this post.
http://community.research.microsoft.com/blogs/alpineinker/archive/2008/04/06/inkseine-doesnt-work-with-windows-search-4-preview-via-the-best-bug-report-ever.aspx
The upshot is that we can't fix this - it's a bug in the WDS 4.0 Preview that InkSeine is tripping. But we expect this bug to be fixed in the "real" release of WDS 4.0 - not sure when that will be though.